What was the objective of this study?

• The main purpose of this investigation was to develop an adaptation for Spanish-speaking populations of the self-administered cognitive screening tool ‘Test Your Memory’ (TYM).
• The TYM was originally created at the Addenbrooke’s Hospital in Cambridge, UK.

Design of the TYM

• The TYM assess the 10 domains that are specified in the following figure.

  

Test Your Memory - Spanish Version (TYM-S)

• The Test Your Memory - Spanish Version (TYM-S) was developed in a cohort of Chilean patients with mild cognitive impairment, patients with diferent forms of dementia and healthy controls.
• A copy of the adaptation for Spanish-speaking populations carried out can be seen in the following slide.

What resutls did the TYM-S show then?

• 74 Chilean subjects, including 14 patients with mild cognitive impairment, 30 patients with dementia (mainly Alzheimer’s disease) and 30 cognitively healthy controls matched by age, years of education and sex were assessed with the TMY-S and other neuropsychological tests.

• Dementia and mild cognitive impairment patients performed significantly worse than controls on the TYM-S (see the figure below).

  

  see the figure below

• In terms of convergent validity, the TYM-S correlated significantly with other assessments of global cognitive efficiency, executive functions, dementia severity, functional performance in activities of daily living and cognitive change (see the figure presented in the next slide).

• Concerning reliability, the TYM-S showed a high index of internal consistency (Cronbach’s alpha = 0.918).

• In relation to its diagnostic accuracy, ROC curve analyses suggested a cut-off point of 39 for the TYM-S to discriminate between cognitively healthy controls and patients with dementia with a sensitiviy of 0.931 and a specificity of 0.862 (area under the curve = 0.963) (see the figure presented in the next slide).
• A cut-off point of 44 was estimated for the TYM-S to discriminate between cognitively healthy controls and patients with mild cognitive impairment with a sensitiviy of 0.857 and a specificity of 0.690 (area under the curve = 0.826) (see the figure presented in the next slide).

Questions?

• Please, click here to find out more about this paper!
• Also, do not hesitate to email me (carlos.munoz@sheffield.ac.uk) in case you would like to discuss further any issue about this publication…